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Internal siliconization


Siliconization is realized with an aqueous emulsion of a polydimethysiloxanic oil, conforming to all pharmacopeias, sprayed inside the vials. The silicone film is fixed onto glass through the annealing lehr. All vials from 5ml to 1L, clear or amber, Type I, II or III glass may be siliconized. To maintain the quality of the coating, siliconized vials should be stored in dry condition and at moderate temperature.
Silicone breaks down at temperature over 350° C.

Major qualities products for pharmaceutical

  • It provides a protective layer useful for fragile molecules, further minimizing the interactions between the product and the container

  • It prevents high viscosity infusions from sticking to the internal surface of the vials giving them a perfect transparency

  • Finally, due to its hydrophobic properties, the silicone coating ensures a higher restitution rate down to the last drop of product

  • Compatibility tests between the product formulation and the siliconized vials have to be performed. The resistance of the silicone coating depends on the chemical structure of the pharmaceutical product, as well as its dissolving power on silicone. 

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